关键词: 肝癌, 腹腔镜, 肝左叶部分切除, 生存分析

Abstract: 【Abstract】〓Objective〓To evaluate the short- and long-term efficacy of laparoscopic partial left liver resection for treatment of hepatocellular carcinoma. Methods〓The clinical data of 51 patients who received laparoscopic partial left liver resection(laparoscopic group) were retrospectively compared with 50 patients who underwent open partial left liver resection (open group) from May 2008 to June 2012. The duration of operation, intraoperative blood loss, hospital stay, postoperative complications, hospital cost and the rate of survival and recurrence were compared respectively. Results〓The duration of opera-tion was longer in laparoscopic group than that in open group(128.6±29.7 min vs 106.3±26.5 min, P<0.05), the blood loss during operation was more than that in open group (180.5±53.6 ml vs 130.2±44.5 ml,P<0.05)..Average hospital stay in laparoscopic group was shorter than that in open group (6.8±1.4 d vs 11.4±3.0, P<0.05)..Total hospital cost in laparoscopic group was lower than that in open group(P<0.05). The rate of postoperative complications between the two groups was not statistically significant..The median overall survival time was 40 months in laparoscopic group and 41 in open group. The 1-, 2- and 3-year survival rate was 90.2%, 80.4%, 68.6%, respectively in laparoscopic group and 90.0%,.82.0%,.66.0% in open group. The median disease-free survival time was 29 months in laparoscopic group and 31 in open group. The 1-,2- and 3-year recurrence rate was 19.6%,45.1%, and 54.9%, respectively in laparoscopic group and 22.0%,42.0% and 50.0% in open group..Conclusion〓Laparoscopic partial left liver resection is safe and feasible,.and has similar effect on prognosis of patients with hepatocellular carcinoma. When Compared with open surgery. and laparoscopic surgery have some advantages, including minimally invasive,.faster recovery,.shorter hospital stay and lower cost.

Key words: Hepatocellular carcinoma, Laparoscopy, Partial left liver resection, Survival analysis