关键词: 粗针穿刺活检, 甲状腺结节, 超声造影

Abstract: 【Abstract】 Objective To evaluate the diagnostic value of contrast-enhanced ultrasound combined with ultrasonography-guided core-needle biopsy (US-guided CNB) of thyroid nodules. Methods Contrast-enhanced ultrasound and US-guided CNB were performed in a total of 89 nodules from 81 patients. All ultrasound findings and pathological results of both needle biopsies and surgical specimens were reviewed. Results The sensitivity, specificity and accuracy of contrast-enhanced ultrasound were 86.7%,95.8%,and 91.0% respectively in differentiation between benign and malignant thyroid nodules. US-guided CNB could get almost all the lesions. Nearly 98.9% of the pathological results of needle biopsies were in accordance with these of surgical specimens. Conclusion Contrast-enhanced ultrasound is effective in detecting malignant thyroid nodules. Contrast-enhanced ultrasound combined with US-guided CNB is an accurate, safe and simple diagnostic method for differentiating thyroid diseases, and which is worthy to recommend widely.

Key words: Contrast-enhanced ultrasound, Core-needle biopsy, Thyroid nodules