关键词: 罗哌卡因, 布比卡因, 老龄患者, 下肢手术

Abstract:

【Abstract】 Objective To investigate the anesthesia effect of middle-dose ropivacaine and bupiva-caine for lower limb operation in aged patients. Methods Fifty of agedtranscervical fracture patients who underwent surgical treatment were randomized into ropivacaine groupand bupivacaine group (n=25 each). The patients were given combined spinal epidural anesthesia (CSEA) by injection of 0.5%ropivacaine 2.5 mL or 0.5%bupivacaine 2.5 mL through subarachnoid cavity..During the anesthesia,2% lidocaine was added when the anesthesia effect was insufficiency. During the operation, the status of respiration and circulation were monitored for the evaluation of anesthesia effect and adverse reaction. Results The differences of anesthesia effect, maximum blockage plane and adverse reaction were insignificant between the two groups.(P>0.05)..The decrease of blood pressure was obvious in bupivacaine group(P<0.05). Ropivacaine group was slow in starting sensation blockage and had short duration,.and had mild motion blockage.(P<0.05).compared with those in bupivacaine group). Conclusion Both ropivacaine and bupivacaine had anesthetic effect for lower limb operation in aged patients. Ropivacaine is more suitable for the aged patients for its less effect on circulatory system, mild motion blockage and rapid recovery of motion blockage.

Key words: Ropivacaine, Bupivacaine, Aged patients, Lower limb operation