关键词: 微创经皮肾穿刺取石术, 应激反应, 肾结石, minimally invasive percutaneous nephrolithotrips, renal calculus, stress

Abstract: Objective To explore the effect of minimally invasive percutaneous nephrolithotrips(MPCNL) on stress response of patients with renal calculus . Methods we retrospectively analyzed 82 cases of renal calculus from February,2004 to October,2008 in our hospital with 46 with MPCNL (MG) and 36 with open operation (OG) . peripheral blood samples were obtained preoperatively and 3 h, 24 h after operation for measuring cortisol, IL-6, C-response protein and glucose. Result The levels of cortisol, IL-6, CRP and glucose in both OG and MG were remarkably higher at 3 h postoperatively than that at preoperation, The levels of cortisol, IL-6, CRP and glucose in the OG was much superior to the MG (P<0.05). Conclusion The results of this study indicate that minimally invasive percutaneous nephrolithotrips imposes less influence on stress response of patients with renal calculus than the OG.This might suggest the quick recovery of the patients receiving MPCNL.