关键词: 腹股沟疝, 疝囊, 细菌

Abstract: Objective To investigate whether local thickening of inguinal hernia sac is related to bacterial infection. Methods From June 2015 to December 2016, 68 patients diagnosed as inguinal hernia in the Sixth Affiliated Hospital of sun Yat-sen University were selected. According to whether the hernia sac was thickened or not, the hernia sac was divided into thickened group and smooth group. The tissue structure composition and inflammatory cell count of the two groups were observed and compared, and the presence of bacterial DNA was detected by real-time fluorescence quantitative PCR. Results The incidence of internal lateral thickening of the hernia sac was 66.1% （37/68）, which was related to the course of disease （disease course <1 y 39.1%,1 y~5 y 46.1%,>5 y 84.2%）, previous incarceration （75% vs. 45.8%） and adhesion （95% vs. 37.5%）. Microscopic observation of the thickened hernia sac showed thickened fibrous connective tissue with more inflammatory cell infiltration（Neutrophils 15.2±2.3 vs. 2.5±0.7, lymphocytes 35.3±1.9 vs. 12.8±1.4, plasma cells 2.6±0.6 vs. 1.5±0.4, a total of 53.1±1.3 vs. 16.8±1.2, P < 0.05） and telangiectasia （67.6% vs. 25.8%, P<0.05）. DNA expression of e. coli was positive in 2 cases in the thickening group and 1 case in the smooth group. Conclusion Inguinal hernias, especially those with a long course and history of incarceration, may have local bacterial infection.

Key words: inguinal hernia, hernia sac, bacteria