即时检测全血降钙素原在急诊感染患者的应用价值

doi:10.3969/j.issn.1009-976X.2020.06.014

摘要/Abstract

摘要： 目的评估即时检测（POCT）全血降钙素原（PCT）应用于急诊临床的可行性。方法采用POCT法对疑诊感染患者的全血标本进行PCT测定,将结果与中心实验室检测结果进行对比。结果与中心实验室相比,POCT法显著缩短了临床周转时间（TAT）。通过kappa检验对两种方法获得的结果进行一致性分析,结果表明,以0.5 ng/mL和2ng/mL为临界点,kappa系数分别为0.786和0.923,两种检测方法所得结果一致性较好。结论 POCT法检测PCT快速可靠,适用于急诊临床工作。

关键词: 即时检测, 周转时间, 降钙素原

Abstract: Objective The feasibility of point-of-care testing（POCT） for procalcitonin （PCT）in emergency clinical work was assessed. Methods PCT determination of whole blood samples from patients with suspected infection was implemented by POCT. The results from POCT were compared with that from a central laboratory. Results The clinical Turn-around Time （TAT） of PCT determination were significantly shortened by POCT. Consistency analysis of the results obtained by the two methods was carried out by kappa test. With 0.5 ng/mL and 2 ng/mL: as the critical points, the kappa coefficients are 0.786 and 0.923, and the results obtained by the two detection methods are highly consistent. Conclusion Determination of PCT by POCT is fast and reliable and it is suitable for emergency clinical work.

Key words: procalcitonin, point-of-care testing, turn-around time

中图分类号:

R446

冯碧娟, 施旖旎, 钟裕兰, 吴浩, 余涛, 陈飞霞. 即时检测全血降钙素原在急诊感染患者的应用价值[J]. 岭南现代临床外科, 2020, 20(06): 753-756.

FENG Bi-juan, SHI Yi-ni, ZHONG Yu-lan, WU Hao, YU Tao, CHEN Fei-xia. Application of point-of-care testing for procalcitonin in emergency clinical work[J]. Lingnan Modern Clinics in Surgery, 2020, 20(06): 753-756.

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