FOLFOX方案肝动脉灌注化疗的研究进展

doi:10.3969/j.issn.1009-976X.2023.04.011

摘要/Abstract

摘要： 肝动脉灌注化疗（HAIC）是肝癌的重要治疗手段之一。近年来中国学者通过不断探索,创新性地将以奥沙利铂为基础的FOLFOX方案应用于肝癌灌注化疗中,FOLFOX-HAIC及其联合方案在治疗中晚期肝癌中取得了令人鼓舞的成果,得到越来越多的重视。本文总结分析国内外相关文献报道,对FOLFOX-HAIC的发展历史、临床应用、研究进展及目前存在的问题等方面进行综述。

关键词: 原发性肝癌, 肝动脉灌注化疗, FOLFOX方案, 联合治疗, 奥沙利铂

Abstract: Hepatic arterial infusion chemotherapy （HAIC） is one of the important treatments for hepatocellular carcinoma. In recent years, through continuous exploration, Chinese scholars have innovatively applied the oxaliplatin-based FOLFOX regimen to perfusion chemotherapy for hepatocellular carcinoma, and FOLFOX-HAIC and its combination regimen have achieved encouraging results in the treatment of intermediate to advanced hepatocellular carcinoma, which has received increasing attention. This paper summarizes and analyzes the results reported in the relevant domestic and international literature, and reviews the development history, clinical applications, research progress and current problem of FOLFOX-HAIC.

Key words: hepatocellular carcinoma, hepatic artery infusion chemotherapy, FOLFOX, combination therapy, oxaliplatin

中图分类号:

R735.7

钱均霖, 汤宏涛, 林葳, 胡泽民. FOLFOX方案肝动脉灌注化疗的研究进展[J]. 岭南现代临床外科, 2023, 23(04): 347-352.

QIAN Jun-lin, TANG Hong-tao, LIN Wei, HU Ze-min. Research progress of hepatic arterial infusion chemotherapy with FOLFOX regimen[J]. Lingnan Modern Clinics In Surgery, 2023, 23(04): 347-352.

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