关键词: 下肢深静脉血栓形成, 导管溶栓, 支架置入, 血栓形成后综合征

Abstract: Objective To investigate the clinical efficacy on treatment of lower extremity deep venous thrombosis with thrombolysis combined with iliofemoral vein stenting and anticoagulation. Methods The data of 79 cases were analyzed from June 2016 to January 2019. And the patients were divided into operation group and anticoagulation group according to different treatment methods. The short-term and long-term treatment effect, and stent patency were compared and analyzed. Result There were 31 patients in the operation group and 48 patients in the anticoagulation group. The average decrease of the circumference of the 10 cm below the patella in the operation group was （4.83±1.26） cm, and that in the anticoagulation group was （2.75±0.82） cm, and the difference was statistically significant. At average of 18 months′ follow-up, the incidence of PTS in the operation group was 25.8% compared with 57.8% in control group（P=0.004）. The overall primary patency of stent was 80.6%. The average onset time of the operation group was 5.2 days, while the average villalta score was 6.5. The pearson correlation analysis showed that the onset time was positively correlated with Villalta score, indicating that the earlier the thrombus was treated the better outcome would be concluded. Conclusion CDT combined with stenting is a safe and effective method for the treatment of acute deep venous thrombosis of lower extremities, and the incidence of post thrombotic syndrome is low.

Key words: DVT, CDT, stent, PTS