关键词: 抗凝, 心房颤动, 急性肠系膜上动脉栓塞

Abstract: Objective To investigate clinical manifestation of acute mesenteric arterial embolism（AMAE） in patients with atrial fibrillation. Methods The retrospective study was performed on the clinical data of atrial fibrillation with acute mesenteric arterial embolism admitted into the Sun Yat-sen Memorial hospital of Sun Yat-sen University from January 2009 to January 2019. Results 15006 patients with atrial fibrillation were retrieved， of 13 cases received AMAE and the incidence was 0.087%. 8 cases were males and 5 were females. The ages range from 46 to 87 and the average age was 65.5±5.3 years old. 41 AMAE patientswere retrievedand the incidence of atrial fibrillation was 31.72%（13/41）. Belly pain was all the starting symptom of AMAE， with no characteristic signs and test results. The average time from seeking medical advice to making a definite diagnosis was 47.9 hours. The total mortality was 46.15%（6/13）， with death of 3 for 8 patients received surgery and death of 3 for 5 patients received conservation treatment. Just 2 patients took anticoagulant drugs，one was warfarin and the other was rivaroxaban， but none of the coagulation indicators met the standard. Conclusion AMAE is a rateof atrial fibrillation， while atrial fibrillation is the risk factor for AMAE. Age， lack of specific signs and test indicator result in a long diagnostic period and high mortality. Doing CTA or DAS as a valuable supplementary approach timely to make a definite diagnosis as early as possible， accurate judgment of illness to make a appropriate therapy decision and taking anticoagulant drugs regularly is effective in decrease of morbidity and mortality.

Key words: anticoagulation, acute mesenteric arterial embolism, atrial fibrillation