关键词: 体温, 机器人腹腔镜手术, 凝血功能, 膀胱癌, 加温输液

Abstract: ［Abstract］ Objective To investigate the effect of intraoperative warming infusion on temperature and coagulation function in patients undergoing robot?assisted laparoscopic radical surgery for bladder cancer. Methods A total of sixty patients undergoing robot?assisted laparoscopic radical surgery for bladder cancer， aged 18~65 years， ASA between Ⅰ and Ⅲ， were randomly divided into control group and warming infusion group， 30 cases in each group. Patients in control group underwent routine temperature preservation measures （room temperatures set above 24°C， patients covered with the quilts， the peritoneal rinse pre?heated before irrigation， and resuscitation of temperature after surgery）|based on the same measures as those in control group， patients in warming infusion group performed continuously warming infusion during anesthesia and surgery， setting the temperature at 41℃. The perioperative core body temperature （temperature of nasopharynx） and changes of coagulation parameters such as PT， APTT， TT， Fib， and PLT were recorded. Results Body temperatures of patients in control group decreased progressively to 35°C at the conclusion of surgery， with significantly different from those of warming infusion group at the points except the baseline value and 1 h after surgery（P<0.05）. However， patients in warming infusion group maintained their temperature within a normal range. The prolongation time of APTT in control group was greater than that of warming infusion group（P<0.05）， and the shortening time of TT was greater than that of warming infusion group（P<0.05）. There was no significant difference between the two groups with respect to PT， Fib and PLT. Conclusion During the robot?assisted laparoscopic radical surgery for bladder cancer， continuously warming infusion can maintain the patient′s temperature within a normal range and avoid the coagulation disorder induced by hypothermia， which is worthy of popularization in clinic.

Key words: robot?assisted laparoscopic surgery, temperature, bladder cancer, warming infusion, coagulation function