关键词: 缺血, 骨骺, 腓骨近端

Abstract: ［Abstract］ Objective To investigate the effect of ischemia on epiphyseal plate of proximal fibula. Methods Twelve young rabbits of 8 weeks old were randomly divided into 3 groups. The proximal blood vessels of the fibula were carefully exposed according to the cutting method of transplantation of fibula with epiphysis. The blood supply to the proximal epiphysis of the fibula was blocked by 0， 1 and 1.5 hours by blocking the right common iliac vessels. X-ray examination was performed every week after operation to observe and record the time of epiphyseal closure of fibula. Statistical analysis was used to compare the closure time of fibula epiphysis in each group. Results the closure time of epiphysis in 0 hour ischemia group was 8.25±0.71 weeks， the closure time of epiphysis in 1 hour group was 8.13+0.99 weeks， and the closure time of epiphysis in 1.5 hour ischemia group was 8.13±0.99 weeks. There was no significant difference in the closure time between the three groups （P>0.05）. Conclusion In the process of epiphyseal fibula transplantation， if the time of epiphyseal ischemia is controlled within a certain time， the short term epiphyseal ischemia would not lead to premature closure of epiphysis.

Key words: rabbits, proximal fibula, ischemia, epiphysis