关键词: 脑脊液, 乳酸, 降钙素原, 颅内感染

Abstract: ［Abstract］ Objective To explore the diagnostic value of cerebrospinal fluid procalcitonin （PCT） and lactic acid level in intracranial infection after craniotomy. Methods Forty post?craniotomy patients with suspicious intracranial infection were chosen in our study； these patients were divided into infected group and disinfected group （n=20/each group）. PCT and lactic acid level in the serum and cerebrospinal fluid were detected and analyzed， respectively. Results Both PCT and lactic acid values in the cerebrospinal fluid and PCT in serum in the infected group were significantly higher than those in the disinfected group （P<0.05）. Both PCT and lactic acid in the CSF had good sensitivity and high specificity. Conclusion CSF PCT could be proposed as an effective diagnostic marker for intracranial infection and it is superior to CSF lactic acid， serum PCT and lactic acid count.

Key words: procalcitonin, intracranial infection, lactic acid, cerebmspinal fluid