关键词: 肝癌, 个性化治疗, 肝细胞肝癌, 早期诊断

Abstract: ［Abstract］ Hepatoma ranks the sixth in the incidence of cancer and the second in the global tumor?related mortality. Patients with hepatoma have an extremely low survival rate due to difficult early diagnosis, rapid disease progression and lack of targeted drugs. Early detection of hepatocellular carcinoma （HCC）is greatly limited due to the wide variety of risk factors（including genetic susceptibility, morphological diversity and microenvironment）. Therefore, based on the heterogeneity of individual patients with hepatoma, precision medicine provides a new perspective for individualized diagnosis and targeted treatment of cancer, and even enables us to carry out pre?clinical screening of tumors in high?risk groups. This paper reviews the advances in the early diagnosis, molecular classification, signal disorders and individualized treatment of hepatoma.

Key words: early diagnosis, hepatocellular carcinoma, hepatoma, individualized treatment