关键词: 负压引流技术, 银离子敷料, 糖尿病足, 溃疡

Abstract:

Objective To explore the safety profile and efficacy of silver ion dressing combined with vacuum sealing drainage in the treatment of diabetic foot ulcer. Methods Totally 110 cases with diabetic foot ulcer in our hospital from December 2014 to December 2016 were randomized into observation group （55 cases） and control group （55 cases）. The observation group were treated with silver ion dressing combined with vacuum sealing drainage, while the control group were treated with conventional debridement combined with Vaseline gauze. Compared with the wound healing, dressing time, hospitalization time, VAS score and clinical efficacy. Results The appeared time of fresh granulation tissue, wound healing time, dressing change times and hospitalization time of the observation group were significantly less than the control group（6.74±1.86 vs 10.55±1.73 d, 33.04±5.82 vs 42.29±4.77 d, 8.87±2.85 vs 20.29±3.06 times, 15.38±5.51 vs 22.08±4.85 d, all P values<0.05）, the wound reduced area of the observation group was significantly higher than that of control group（48.83 ± 7.37 vs 34.49 ± 6.94%, P<0.05）. The VAS score of observation group and control group after treatment was significantly lower than those before treatment（2.71±1.39 vs 5.44±1.58, 4.13±1.44 vs 5.51±1.49, all P values<0.05）. The VAS score of observation group after treatment was significantly lower than the control group （2.71 ± 1.39 vs 4.13 ± 1.44, P<0.05）. The effective rate of observation group was significantly higher than the control group （90.91% vs 66.45%, P<0.05）. Conclusion Silver ion dressing combined with vacuum sealing drainage can effectively cure diabetic foot ulcer, promote the rehabilitation of patients, which is worthy of clinical application.

Key words: silver ion dressing, vacuum sealing drainage, ulcer, diabetic foot