关键词: 利多卡因, 氧气流量, 雾化吸入 , 气道表面麻醉

Abstract:

 Objective To investigate the effect of different oxygen flow rate on airway surface anesthesia with nebulized lidocaine. Methods Seventy-five patients with difficult airways undergoing awake tracheal intubation, in accordance with the random number table, were divided into 3 groups（n= 25 each）. Patients in all groups inhaled 2% lidocaine 10 ml for airway surface anesthesia, but the oxygen flow rate between three groups was different. The oxygen flow rate was 3 L/min in group A, 6 L/min in group B and 9 L/min in group C. Awake tracheal intubation guided by fibrotic bronchoscope was performed at the end of inhalation. The intubation condition and the tolerance to tube were assessed, success rate and time of intubation, together with adverse effects and complications were recorded. Results The intubation condition and the tolerance to tube of group B was significantly better than that in group A and group B（Ρ <0.05）. The first-attempt success rate and time of intubation in group B were significantly higher than that in group A and group C（Ρ <0.05）, and there was no significantly difference between group A and group C. Conclusion The effect of airway surface anesthesia by inhaling quantitative lidocaine for awake tracheal intubation was better when the oxygen flow rate was 6 L/min.

Key words: oxygen flow rate, lidocaine, nebulized inhalation, airway surface anesthesia