关键词: 侵袭, 甲状腺癌, 转移, microRNA

Abstract: 【Abstract】 To summarize the relationship of microRNA（miRNA）to metastasis and invasion of thyroid cancer. Domestic and international publications involving the relationship of miRNA to thyroid cancer were screened and reviewed. miRNA played a key role in the process of thyroid cancer metastasis. According to its function, it could be distinguished from cancer-promoting gene（such as miR-221, miR-222, miR-146b, etc. ）to suppressor gene（such as miR-199a, miR-204, etc. ）. The more detailed experimental studies about the relationship of miRNA to metastasis and invasion of thyroid cancer need to be researched in order to provide a new method for the diagno sis and treatment of thyroid cancer metastasis and invasion.

Key words: Metastasis, MicroRNA, Invasion, Thyroid cancer