关键词: 介入治疗, 术前治疗, 局部晚期乳腺癌

Abstract: 【Abstract】 Objective To investigate the effect of preoperative arterial infusion chemotherapy with embolism on locally advanced breast cancer. Methods Thirteen patients with locally advanced breast cancer diagnosed by the core needle biopsy from February 2010 to March 2015 in this hospital were selected. Seldinger procedure was used to perform angiography by arterial femoralis. Super-selective arterial catheterization was performed to ensure the locally infusion of Epirubicin 100 mg, Mitomycin 10 mg, 5-FU 1 g plus Oxaliplatin 1 g, finally the tumor blood supply artery war embolizated. Results Of 13 cases, two patients achieved CR, ten patients achieved PR, one patient achieved SD. The rate of CR+PR was 92.3% and CR + PR + SD was 100% . All the 13 patients received radical mastectomy. Conclusion Preoperative arterial infusion chemotherapy is effective and safe in the treatment of locally advanced breast cancer.

Key words: Locally advanced breast cancer, Preoperative chemotherapy, Arterial infusion chemotherapy