关键词: 腋窝手术, 前哨淋巴结活检, 早期乳腺癌

Abstract: 【Abstract】 Objective To summarize the surgical experience of sentinel lymph node biopsy in early staged breast cancer. Methods Retrospectively analyzed the clinical data of 78 patients with early stage breast cancer undergone sentinel lymph node biopsy in our hospital from January 2013 to December 2015. Results A total of 78 patients suffering from breast cancer were enrolled. Mean age was 54 years （range 32-75）. Of 78 cases, the lesion was localized on the right breast in 48（62%）, while was localized on the left breast in 30（38%）. Also, the tumor involved the upper-outer quadrant in 46（59%）patients, the lower external quadrant in 13（17%）, the upper-inner quadrant in 11（14%）and the inferior-internal quadrant in the remaining 8（10%）. All removed breast lesions were histologically malignant: 55（70%） patients diagnosed as infitrating ductal carcinoma（IDC）, 16（21%）ductal carcinoma in situ（DCIS）, 5（6%） infiltrating lobular carcinoma（ILC）and 2（3%）as mixed invasive cancer. The successful rate of SLNB is 90%（70）, in which pathological positive rate of SLNB was 34%（24）, while pathological negative rate of SLNB was 66%（46）. Medium follow-up was 12 months, and only one case developed axillary recurrence. Conclusion Sentinel lymph node biopsy is a safe and effective way to evaluate the status of axillary and the good results are obtained when undertaken by an experienced surgeon.

Key words: Sentinel lymph node biopsy, Axillary surgery, Early stage breast cancer