关键词: 胰十二指肠切除术, 胰漏, 对比研究

Abstract: 【Abstract】〓Objective〓To evaluate the incidence rate of pancreatic leakage relative to three different pancreaticojejunostomy methods. Methods〓Clinical data of 93 patients who underwent pancreaticoduodenectomy from May 2011 to May 2016 by the same surgeon were retrospectively analyzed. Of the cases, 42 cases were performed pancreatico-jejunal end-to-end anastomosis (Group A). And 51 cases underwent end-to-side anastomosis, in which, 36 (group B2) underwent end-to-side mucosa-to-mucosa anastomosis,while the other 15 (group B1) underwent end-to-side anastomosis because of the limited diameter of pancreatic duct. Results〓The incidence rate of pancreatic leakage in group A,group B1 and group B2 were 2.52%, 20% and 0.00% respectively,and there was significant difference between the three groups (P>0.05). Conclusion〓There was significant differences in the incidence of pancreatic leakage between the group A, group B1 and group B2. The incidence rate was high in the end-to-side anastomosis group (group B1). Appropriate anastomosis method should be selected according to the condition of pancreas in order to reduce the incidence rate of pancreatic leakage.

Key words: Pancreaticoduodenectomy, Pancreatic leakage, Comparative study