关键词: 全身, 术后认知功能障碍, 麻醉, 相关因素

Abstract: 【Abstract】 Objective〓To observe the related factors of postoperative cognitive dysfunction in patients with non-cardiac surgery after general anesthesia. Method〓267 non-cardiac surgery patients under general anesthesia were included in this study. The patients with POCD were assigned to PD group and those without POCD were served as NPD group. Perioperative information of the patients were recorded. Logistic regression was used in the statistical analysis to the occurrence of postoperative cognitive disorder before and after operation. Results〓Postoperative cognitive disorder was related to age, ASA grade, smoking history, amount of bleeding, premedication, length of operation time, blood transfusion, dosage of remifentanil, dosage of isoflurane, the hypotension of intraoperative period, the hypertension of postoperative period, high VAS scores. Conclusion〓The patients age, length of operation time, the hypotension of intraoperative and the VAS score are the risk factors of postoperative cognitive disorder.

Key words: Postoperative cognitive disorder, General, Related factors, Anesthesia