关键词: 超声光散射成像, 乳腺癌, 彩色多普勒超声

Abstract: 【Abstract】〓Objective〓To investigate the value of diffused optical tomography with ultrasound localization in the diagnosis of breast lesions. Methods〓Diffused optical tomography with ultrasound and color Doppler ultrasound were used to test 408 lesions in the 263 patients with breast diseases. The diagnosis of breast cancer from diffused optical tomography with ultrasound and color Doppler ultrasound were compared with that from postoperative pathological findings. The sensitivity, specificity and accuracy were analyzed. Results〓The sensitivity, specificity, false negative rate, misdiagnose rate and accuracy in diagnosing breast cancer using diffuse optical tomography with ultrasound were 97.4%, 82.4%, 2.6%, 17.6%, 83.8%, respectively. The sensitivity, specificity, false negative rate, misdiagnose rate and accuracy in diagnosing breast cancer using color Doppler ultrasound were 94.7%, 62.7%, 5.3%, 37.3%, 65.7%, respectively. There were significant differences in specificity, misdiagnose rate and accuracy between the both. Conclusion〓Diffuse optical tomography with ultrasound, as an assistant diagnostic tool for breast diseases, improves the specificity and accuracy of diagnosing, and reduces misdiagnosis.

Key words: Color doppler ultrasound, Diffuse optical tomography with ultrasound, Breast cancer