关键词: 结肠、直肠癌, 腹腔镜, 疗效

Abstract: 【Abstract】〓Objective〓To compare the clinical effects between laparoscopic versus open radical resection for colorectal cancer. Methods〓A retrospective clinical data of 320 cases during the period from 2009 July to 2014 December were analyzed. Among them, 156 patients underwent laparoscopic radical resection of colorectal cancer (laparoscopic group), 164 cases of patients with open radical resection of colorectal cancer (laparotomy group). The number of lymph node dissection, length of incision, operation time, intraoperative bleeding, postoperative anal exhaust time, postoperative intestinal function recovery time, complications, hospitalization stay were observed and compared between the two groups. Results〓The number of lymph node biopsy in laparoscopic group and laparotomy group respectively were 12.89±3.44 and 14.33±3.38, no significant difference were found between the two groups (both P>0.05). The length of incision in laparoscopic group and laparotomy group were 5.10±1.60 cm and 15.2±2.51 cm. The operation time was 196.75±21.54 min and 153.82±14.85 min. The amount of bleeding was 85.63±35.73 ml and 182.02±65.73 ml respectively. Out-of-bed activity time was 4.0±1.41 and 6.8±1.82 days. The time of anus exhaust were 2.63±1.33 and 4.70±1.39 days. The length of hospital stay were 10.76±2.10 and 16.42±1.95 days, and total cost of hospitalization were 3.69×104±3000 and 3.03×104±3700 yuan. Compared between two groups, the differences were statistically significant (all P<0.05). Incidence of complications was found no difference between the two groups (5.8% vs 12.1%,P>0.05). Conclusion〓In this study, compared with the traditional open operation, laparoscopic resection of colorectal cancer was safe and effective, with advantage of less trauma and faster recovery, the long-term therapeutic efficacy was comparable with open operation.

Key words: Colorectal cancer, Radical resection, Laparoscopy, Efficacy