关键词: 肾结石, 经皮肾取石术, 重症脓毒症, 有效途径

Abstract: 【Abstract】〓Objective〓To investigate risk factor of post percutaneous nephrolithotomy (PCNL) sepsis. Methods〓A retrospective analysis from June 2004 to June 2014 was performed in 9332 cases with kidney stones. All patients underwent surgical procedure of percutaneous nephrolithotomy and postoperative urinary-derived sepsis was found in 93 cases. The age, gender, presence of urinary tract infection, and preoperative percutaneous renal surgery time and a series of factors associated with sepsis were analyzed. Results〓Through a one-way factor analysis, female patients (P<0.05), stones> 20 mm (P<0.05), history of diabetes (P<0.05), not the use of antibiotics (P<0.05) and preoperative percutaneous nephrolithotomy were associated with PCNL sepsis. Multivariate regression analysis showed that female patients (P<0.05), history of diabetes (P<0.05) were risk factors for PCNL sepsis. Of 93 cases, 82 were cured, 11 died of disseminated intravascular coagulation and multiple organ dysfunction. Conclusion〓Women and history of diabetes are risk factor to induce to PCNL sepsis. The high-risk patients deserve the standard preoperative antibiotic preparation.

Key words: Kidney stones, Percutaneous nephrolithotomy, Severe sepsis, Effective way