关键词: 肺癌, 胸腔镜, 快速康复外科, 效果

Abstract: 【Abstract】 Objective〓To evaluate effects of thoracoscopic surgical treatment combined with application of fast-track surgery principles on lung cancer surgery. Methods〓A total of 80 patients who underwent radical resection of pulmonary carcinoma between August 2013 and August 2014 were selected, and divided into observation group and control group with 40 patients in each group. The patients in observation group were treated through the application of fast-track surgery principles, while the controls were treated with thoracoscopic chest surgery. The pain recording at 1 d, 3 d, 7 d, and 14 d after operation was scored by visual analogue scale (VAS). The postoperative retention times of urinary catheter and chest tube,times to passage of gas by anus,lengths of stay,and incidence of complications were counted. And the serum interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) contents were assayed at 1 d, 3 d, 7 d, 10 d, and 14 d after admission. Results〓The patients of the observation group had shorter retention times of urinary catheter and chest tube, time to passage of gas by anus, and length of stay than those of the control group (all P<0.05). The patients of the observation group had lower incidence of postoperative cardiovascular diseases, postoperative infection, and pulmonary infection than that of the control group(P<0.05). The patient of both groups had improved VAS scores at 3 d and 7 d after the surgeries compared with those at 1 d after the surgeries,and the patients of the observation group had greater improving extents than those of the control group(P<0.05). The difference in VAS score at 14 d after the surgeries was statistically insignificant between the patients of the two groups (P>0.05). The differences in serum IL-6 and TNF-α levels at 1d after the operation were statistically insignificant between the patients of the observation group and control group (P>0.05), but the patients of the observation group had significantly lower serum IL-6 and TNF-α levels at 3 d,.7 d,.10 d,.and 14 d than those of the control group.(all P<0.01). Conclusion Thoracoscopic surgical treatment combined with rapid recovery in patients with lung cancer surgery can effectively shorten the postoperative extubation time and length of stay, lighten the degrees of injury and pain, with a lower postoperative complication incidence and faster postoperative recovery.

Key words: Lung cancer, Thoracoscopic, Surgical treatment combined with rapid recovery, Effect