关键词: 痔, 表皮生长因子, 换药

Abstract: 【Abstract】〓Objective〓To observe the clinical effect of epidermal growth factor (EGF) wet-wrap on wound healing after hemorrhoids surgery. Methods〓150 patients with mixed hemorrhoids treated at Sun Yat-sen Memorial Hospital and People?蒺s Hospital of Zhuhai from January 2011 to January 2014 were recruited in this study. All the 150 patients were underwent hemorrhoids surgery and randomly divided into two groups. 78 patients (experimental group) were changed dressing using epidermal growth factor solution gauze and 72 patients (control group) received change dressing using saline gauze. No oral drugs and other topical drugs were used during the wound healing. Wound healing was divided into four grades included cured, markedly effective, effective and invalid. The wound healing was evaluated at the fourteen day after treatment. Results〓The total effective rate of the experimental group was 98.72%, and the control group was 90.28%. The statistical analysis showed that the total effective rate between the two groups was significance different(P<0.05). The average healing time of the experimental group was 12.6±3.16 days (range from 11-16 days) and the control group was 17.9±5.23 days (range from 12-23 days)(P<0.05). Conclusion〓EGF wet wrap can promote skin wound repair, shorten the wound healing time.

Key words: Hemorrhoids, Epidermal growth factor, Dressing