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岭南现代临床外科 ›› 2014, Vol. 14 ›› Issue (01): 73-75.DOI: j.issn.1009-976X.2014.01.021

• 论著与临床研究 • 上一篇    下一篇

直肠癌新辅助化疗病理完全缓解1例并文献复习

吕泽坚1,4,张育超2,3,柳叶青2,3,刘高杰2,3,陈双1,4   

  1. 1. 中山大学孙逸仙纪念医院
    2. 中山大学附属第二医院
    3. 中山大学附属第二医院
    4. 中山大学孙逸仙纪念医院
  • 通讯作者: 陈双
  • 基金资助:

    上皮-间质转化诱导Treg分化加速结肠癌转移的分子机制研究;KLF5表达丢失促进结肠癌EMT和转移的分子机制研究

One case report of pathological complete remission of rectal cancer after neoadjuvant chemotherapy and review of literature

Lv Zejian, Zhang Yuchao, Liu Yeqing, Liu Gaojie, Chen Shuang   

  • Received:2013-07-31 Revised:2013-09-30 Online:2014-02-20 Published:2014-02-20

摘要: 【摘要】〓目的〓探讨进展期结直肠癌新辅助化疗的临床疗效。方法〓报道中山大学孙逸仙纪念医院胃肠外科收治的1例接受新辅助化疗的进展期直肠癌患者的诊疗经过,并复习相关文献。 结果〓经过3疗程的新辅助化疗,患者术后病理结果提示完全病理缓解(pCR)。结论〓新辅助化疗对进展期结直肠癌患者是有效的,适合在进展期结直肠癌患者术前应用。

关键词: 结直肠癌, 新辅助化疗, 病理完全缓解

Abstract: 【Abstract】 Objective〓To explore the clinical efficacy of neoadjuvant chemotherapy for patients with colorectal cancer. Methods〓The diagnosis and treatment course of one case with advanced rectal cancer undergoing neoadjuvant chemotherapy in the Gastroenterology Department, Sun Yat-sen Memorial Hospital of Sun Yat-sen University was reported,and related literature were reviewed. Results〓After three cycles of neoadjuvant chemotherapy,the postoperative pathological result after surgery suggested pathological complete remission (pCR). Conclusion〓Neoadjuvant chemotherapy is effective for the treatment of patients with advanced colorectal cancer, and it is suitable for patients with advanced colorectal cancer before operation.

Key words: Colorectal cancer, Neoadjuvant chemotherapy, Pathological complete remission (pCR)

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