关键词: 导管内乳头状瘤, 超声检查, 乳腺X线摄影术, 纤维乳管镜, 液基薄层细胞学检查

Abstract: 【Abstract】Objective To investigate the clinical and diagnostic characteristics of intraductal papilloma of breast. Methods The clinical data of 663 patients with intraductal papilloma from Jan 2008 to Dec 2010 were analyzed retrospectively. Results The age of this group mainly distributed in 30-50 years old and nipple-discharge was the main clinical characteristic. Some cases were non-palpable breast mass and were detected by ultrasonography and vacuum assisted biopsy. In this group,.there were about 40.2% patients who had positive results in ultrasonography and there were only about 10% patients who had a positive results in mammography. The diagnostic accordance rate of fibro-optic ductoscopy for IP was 98%. The sensitivity and specificity of thinprep cytology test (TCT) for IP were 74% and 96.3% respectively. The average follow-up time of this group was 13.3 months, there were 25 patients who had homolateral recurrence and all of these were multiple intraductal papilloma. Conclusions The main clinical characteristic of intraductal papilloma is nipple discharge and fibro-optic ductoscopy is a preferred diagnostic method for intraductal papilloma..TCT is helpful to increase the diagnostic accuracy. Multiple intraductal papilloma has recurrence rate of 4.5%, so the regular follow-up is necessary.

Key words: Intraductal papilloma, Ultrasonography, Mammography, Fibro-optic ductoscopy, Thinprep cytologic test