关键词: 囊性肾瘤, 多房性囊性肾癌, 免疫组织化学

Abstract: Objective To study the clinicopathologlc features, immunophenotype and differential diagnosis of cystic disease of kidney. Methods 3 cases of cystic diseases were observed under light microscope, HE and immunohistochemical staining. And the literature was reviewed. Results A11 of the three patients presented with loin pain and hematuria．Two cases of cystic nephroma (CN) and one cases of multilocular cystic renal cell carcinoma were identified by pathological method. Cystic nephroma consisted of multilocular cysts and were lined by single epithelial cells. Immunohistochemically, the epithelial cell were positive for cytokeratin and EMA, and the stromal cells were positive for vimentin. Multilocular cystic renal cell carcinoma were lined by single to multilayered epithelial cells with clear cytoplasm. There existed aggressive clear cells between the cysts, which positive for cytokeratin and EMA, and negative for vimentin immunohistochemically. Conclusions Both CN and MCRCC are uncommon renal tumor． There are similar symptoms and images between these two diseases. Pathology is the key to diagnosis. Both of them have good prognosis.