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岭南现代临床外科 ›› 2010, Vol. 10 ›› Issue (01): 57-60.

• 临床研究 • 上一篇    下一篇

脊柱尤文氏肉瘤CT和MR的表现

林笑丰1,陈玥瑶2,袁小平2,杜开利2,谢榜昆2   

  1. 1. 中山二院
    2. 中山大学孙逸仙纪念医院
  • 通讯作者: 林笑丰

CT and MRI Appearances of Spinal Ewing’s sarcoma

  • Received:2009-12-24 Revised:2010-01-22 Online:2010-02-20 Published:2010-02-25

摘要: 目的 探讨脊柱尤文氏肉瘤 (Ewing’s Sarcoma,ES)的CT和MRI表现。方法 回顾性分析经病理证实的7例脊柱ES的影像学资料。 结果 病变累及颈椎、胸椎各3例、腰椎1例。CT检查:2例椎体和/或附件溶骨性骨质破坏,3例椎管内外软组织肿块。MRI检查:7例均表现椎管内外肿物,瘤体T1WI表现为等、低或稍高信号, 6例T2WI表现为不均匀高信号,增强后不均匀强化;1例T2WI为均匀稍高信号,增强后均匀强化。免疫组织化学:肿瘤均表达CD99阳性。 结论 青少年患者进行性发展的椎管内外软组织肿块伴脊柱溶骨性骨质破坏,提示脊柱ES可能。脊柱ES需结合病理学及免疫组化确诊。CT、MRI综合使用为脊柱ES诊断、治疗、疗效评价及预后提供帮助。

关键词: 脊柱, 肉瘤, Ewing, 体层摄影术,X线计算机, 磁共振成像, Spine, Sarcoma, Ewing’s, Tomography, X-ray computed , Magnetic resonance imaging

Abstract: Objective: To study the CT and MRI manifestations of Spinal Ewing’s sarcoma (ES). Methods: From January 2003 to October 2009, the imaging data of 7 cases with spinal ES confirmed by pathology were analyzed retrospectively. Results: The lesions involved cervical, thoracic and lumbar vertebra were in 3, 3 cases and 1 case respectively. CT examination showed that vertebral body and/or appendix osteolytic bone destruction were in 2 cases. Three cases were intra- and extra-spinal soft tissue mass. MRI examination showed that seven cases manifested as intra- and extra-spinal soft tissue mass. T1-weighted image showed low, equal or slightly high signal in 7cases. T2-weighted image showed uneven high signal and contrast image showed heterogeneous enhancement in 6 cases.Only one case had slightly high signal on T2-weighted image and homogeneous enhancement on contrast image. According to immunohistochemical results, CD99 in all cases were positive. Conclusions: Spinal ES should be considered in adolescent patients with aggressive osteolytic bone destruction of vertebrae and intra- and extra-spinal soft tissue mass. The final diagnosis of spinal ES depends on the pathologic and immunohistochemical determinations. CT and MRI should be accurately and synthetically used on spinal ES, which can give more information to diagnosis, treatments, evaluating curative effects and prognosis.

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