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岭南现代临床外科 ›› 2010, Vol. 10 ›› Issue (01): 47-48.

• 临床研究 • 上一篇    下一篇

纳米羟基磷灰石复合材料治疗长骨缺损的临床研究

黄伟奇1,张文通2, 陈勇2,刘胜2   

  1. 1. 广州市荔湾区人民医院
    2. 厦门市中医院
  • 通讯作者: 黄伟奇

Clinical study on the compound material of nanometer hydroxyapatite in the treatment of long bone comminuted fracture

  • Received:2009-11-05 Revised:2010-01-22 Online:2010-02-20 Published:2010-02-25

摘要: 目的 对纳米羟基磷灰石和自体骨治疗四肢长骨粉碎骨折的疗效作出对比,探讨新型复合材料治疗粉碎性骨折的效果。方法 总结2006年至2008年治疗的长骨粉碎性骨折共71例,其中采用自体骨植骨治疗37例,采用纳米羟基磷灰石治疗34例。术后进行随访,观察术后3月、6月、12月的X线检查骨折愈合情况。结果 全部患者均接受12个月以上的随访,自体骨植骨治疗组术后3、6及12月的愈合率为34.9%、69.8%及97.7%,纳米羟基磷灰石植骨治疗组术后3、6及12月的愈合率为32.4%、67.6%及97.3%。两种材料治疗粉碎骨折的骨折愈合率相当(P>0.05),术后关节功能无统计学差异(P>0.05)。结论 纳米羟基磷灰石复合材料可用于填充长骨粉碎性骨折并发的骨缺损,并获得良好的疗效。

关键词: 羟基磷灰石, 粉碎性骨折, 纳米材料, Hydroxyapatite, comminuted fracture, nano-material.

Abstract: Objective To compare the therapeutic efficacy between nanometer material and auto-bone graft in the treatment of long bone comminuted. Methods From June 2006 and July 2008, 71 cases with long bone comminuted fracture received surgical operation were analyzed retrospectively. Among them, 37 cases were treated with auto-bone graft and internal fixation, and 34 cases were treated with nano-material graft and internal fixation.Results All cases were followed up respectively over 12months. In the cases of auto-bone graft, the healing rates were in 34.9%、69.8% and 97.7% within 3, 6 and 12 months, While in the cases of nano-material graft, the healing rates were in 32.4%、67.6% and 97.3%, respectively within 3, 6and 12 months. No significant differences in the bone healing and joint function were found between two groups. Conslusion:Nanometer hydroxyapatite would use in the treatment the long bone comminuted fracture and gained well bone healing.

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