关键词: 近红外光谱技术, 脑灌注压, 生命体征, 颅内压, 高血压脑出血

Abstract: Objective To investigate the effects of near-infrared spectroscopy on intracranial pressure （ICP）， cerebral perfusion pressure （CPP） and vital signs in patients with hypertensive intracerebral hemorrhage before， during and after surgery. Methods Twenty patients with hypertensive intracerebral hemorrhage were monitored for ICP， CPP， brain tissue oxygen saturation （rScO2） and vital signs before and during operation and after operation. Correlation analysis was performed. Results With the progress of the operation， the CPP value of the patients gradually increased， and the ICP value decreased gradually. The difference between the groups was statistically significant （P<0.05）. Preoperative， intraoperative， and postoperative comparisons showed that the ICP of the affected side was lower than that of the healthy side before， during， and after surgery （P<0.05）. ICP was lower than that during surgery and postoperatively. Before （P<0.05）； the postoperative CPP was higher than the healthy side （P<0.05）. There were no significant differences in rScO2， pulse oximetry， heart rate， systolic blood pressure， diastolic blood pressure， mean arterial pressure and body temperature between preoperative， intraoperative and postoperative patients （P>0.05）. Preoperative， intraoperative， postoperative， rScO2 in patients with hypertensive cerebral hemorrhage was negatively correlated with CPP （P<0.05）， and positively correlated with ICP and mean arterial pressure （P<0.05）. Conclusion Near-infrared spectroscopy can timely obtain bleeding in patients with hypertensive intracerebral hemorrhage before， during and after surgery， which is helpful for early diagnosis and treatment.

Key words: near-infrared spectroscopy, cerebral perfusion pressure, intracranial pressure, hypertensive cerebral hemorrhage, vital signs