关键词: 磁共振成像, 胆囊癌, 弥散加权成像, 慢性胆囊炎

Abstract: Objective To evaluate the value of diffusion-weighted imaging （DWI） in the differential diagnosis of benign and malignant gallbladder lesions. Methods A retrospective analysis of 82 cases of postoperative pathologically diagnosed gallbladder lesions， including 58 cases of gallbladder malignant tumors and 24 benign lesions. The difference between ADC values of benign and malignant gallbladder lesions was analyzed by independent t test， and the diagnostic efficacy of ADC value was evaluated by ROC curve. Results The ADC value of gallbladder carcinoma and benign gallbladder lesions was 1.13±0.32×10-3 mm2/s and 1.58±0.33×10-3 mm2/s， respectively. The ADC value of gallbladder carcinoma was significantly lower than that of benign lesions. The area under the ROC curve for the diagnosis of benign and malignant gallbladder lesions was 0.834. When the ADC value was ≤1.38×10-3 mm2/s， the sensitivity of diagnosis of gallbladder cancer was 81.8%， the specificity was 74.1%， and the accuracy was 91.3%. Conclusion DWI has a good application value in the differential diagnosis of benign and malignant gallbladder lesions.

Key words: diffusion-weighted imaging, gallbladder cancer, magnetic resonance imaging, chronic cholecystitis