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岭南现代临床外科 ›› 2019, Vol. 19 ›› Issue (03): 365-368.DOI: 10.3969/j.issn.1009-976X.2019.03.028

• 论著与临床研究 • 上一篇    下一篇

不同肺功能状态下多发肠息肉老年患者进行无痛肠镜的安全性评估

王根保, 张萌, 彭学强, 朱小兵, 欧阳赋斌, 郑少康, 吴论*   

  1. 1.广州中医药大学附属中山医院麻醉科,广东中山 528400;2.中山大学孙逸仙纪念医院全科医学科,广州 510289;3.广州中医药大学附属中山医院肛肠科,广东中山 528400
  • 通讯作者: 吴论
  • 基金资助:
    中山市科技计划项目(社会发展攻关计划(医疗))

Evaluation of simple pulmonary function measurement in elderly patients with painless enteroscopicmultiple polypectomy

WANG Genbao, ZHANG Meng, PENG Xueqiang, ZHU Xiaobing, OUYANG Fubin, ZHEN Shaokang, WU Lun   

  1. 1. Department of Anesthesiology, Zhongshan Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine|2.Department of General Practice, Sun Yat?sen Memorial Hospital, Sun Yat?sen University, Guangzhou 510289|3. Department of Anorectal, Zhongshan Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan 528400, China
  • Online:2019-06-20 Published:2019-06-20
  • Contact: WU Lun

摘要: [摘要] 目的 探讨简易肺功能测定对老年无痛肠镜下多发息肉切除的评估意义。方法 行肠镜息肉切除并能配合简易肺功能测定的老年患者180例,根据术前肺功能检测结果将其分为肺功能正常组A(n=108)108例、肺功能轻中度异常组B组(n=47)及肺功能重度异常组C组(n=25)。比较给药前(T1)、置入肠镜时(T2)、治疗开始10 min(T3)、退镜时(T4)、离开手术室(T5)的心率(HR)、呼吸频率(RR)、平均动脉压(MAP)、血氧饱和度(SpO2)及手术时间、苏醒时间、术后恢复室(PACU)的停留时间、术中麻黄碱、阿托品、丙泊酚的应用量,不良反应,包括呼吸抑制、低血压、体动等。结果 T2与T1时点比较,A组和B组患者MAP、SpO2和HR降低,C组患者时点MAP、SpO2、HR及RR均降低(P<0.05);在T2、T3时间点C组显著低于A组和/或B组(P<0.01);与A、B组比较,C组患者苏醒时间,PACU停留时间延长(P<0.01);三组患者不良反应及应用血管活性药比较,C组患者与A、B组比较,血压下降、呼吸抑制发生率升高,阿托品、麻黄素使用增加(P<0.01)。结论 简易肺功能测定对老年无痛肠镜下多发息肉切除的评估具有重要意义,重度肺功能不全患者行无痛肠镜下息肉切除术不良反应增加。

关键词: 肺功能测定, 肠镜, 老年

Abstract: [Abstract] Objective To explore the value of simple lung function test in elderly patients undergoing painless enteroscopic multiple polypectomy. Methods According to preoperative pulmonary function test results, one hundred and eighty elderly patients were selected and divided into normal pulmonary function (A group, n=108), mild?moderate abnormal pulmonary function (B group, n=47) and severe abnormal pulmonary function (C group, n=25). The heart rate (HR), respiratory rate (RR), mean arterial pressure (MAP), blood oxygen saturation (SpO2) were compared with different time point, pre?dose (T1), colonoscopy (T2), treatment start 10 min (T3), retrospective (T4), leaving the operating room (T5). The operating time, recovery time, and residence time of the postoperative recovery room (PACU) were recorded. Intraoperative ephedrine, atropine and propofol dosage and adverse reactions, including respiratory depression and hypotension, were recorded. Results Compared T2 with T1 time point, MAP, MAP, and SpO2 decreased in group A and group B|however, in group C, all indexes, including MAP, SpO2, HR and RR, decreased in group C (P<0.05). Compared with group A and group B, the recovery time and the residence time of PACU was longer in group C (P<0.01). Compared with group A and B, the incidence of adverse reactions and the use of vasoactive drugs in group C was higher, and the use of atropine and ephedrine increased (P<0.01). Conclusion Patients with pulmonary insufficiency have an increased adverse reaction to polypectomy under painless colonoscopy. Simple lung function tests are important for the assessment of elderly painless intestinal polypectomy.

Key words: pulmonary function test, old age, intestinal polyp, enteroscopy

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