关键词: 危险因素, 手术治疗时机, 坏死性小肠结肠炎, 新生儿

Abstract: ［Abstract］ Objective To analyze the risk factors affecting necrotizing enterocolitis （NEC） in neonates and to explore the surgical treatment timing. Methods A retrospective analysis was performed on 70 cases of NEC children patients and 140 non?NEC neonates in our hospital from January 2013 to December 2018， and univariate analysis and multivariate logistic regression analysis were performed on factors that might affect NEC occurrence， and the treatment methods and results were counted among NECchildren patients. Results There were significant differences between NEC group and non?NEC group in terms of hypertensive disorder complicating pregnancy， prenatal glucocorticoids， premature rupture of membranes， neonatal Apgar score， neonatal weight， combined pulmonary infection， combined sepsis and feeding patterns （P<0.05）. Neonatal Apgar score <7 points， neonatal weight <2.5 kg， combined pulmonary infection and combined sepsis were risk factors for NEC in neonates （P<0.05）， and breastfeeding was a protective factor for NEC in neonates （P<0.05）. Conclusion Influencing factors for NEC in neonates include neonatal Apgar scores， neonatal weight， combined pulmonary infection， combined sepsis and breastfeeding. Children patients with Bell stage Ⅰ and stage Ⅱare given conservative treatment， and children patients with stage Ⅲ stage are treated with surgery as soon as possible， and the surgical timing is suitable within 1 week after the occurrence of NEC

Key words: risk factors, neonates, surgical treatment timing, necrotizing enterocolitis