关键词: 乳腺肿瘤, 麦默通旋切活检, 金属导丝定位活检, 临床触诊阴性

Abstract: ［Abstract］ Objective To evaluate the accuracy and safety of the Clinical application of Mammotome Biopsy system and wire localization in nonpalpable breast lesions （NPBL）. Methods Eighty?four patients with NPBL were randomized into Mammotome Biopsy system group （MMT） and wire localization group （WL） and the diagnosis results， time， bleeding， specimen size， cost and complication were compared between two groups. Results Biopsy was successful in both groups. Compared with WL group， MMT group had shorter operation time， less blood loss and smaller specimen volume， and the difference was statistically significant （P<0.05）. In terms of hospital cost and complication rate， MMT group was significantly higher than WL group （P<0.05）. The diagnostic accordance rate of MMT was 97.6% （41/42）. Compared with WL group （42/42）， there was no significant difference （P>0.05）. In MMT group the positive rate of the incisional margin was higher than WL group. Conclusion For biopsy of NPBL， the Mammotome Biopsy system and the wire localization biopsy have high diagnostic accuracy. In MMT group， it takes less time to perform， has fewer mammary tissue specimen to be removed， has a smaller incision and better cosmetic effect， but it is more expensive and has a higher incidence of complications than the WL group. The positive rate of the incisional margin was higher after the Mammotome Biopsy system. For the diagnosis and treatment of high?risk patients， the choice of wire localization biopsy is more appropriate.

Key words: breast neoplasms, wire localization biopsy, nonpalpable breast lesions, Mammotome Biopsy system