关键词: 玻璃酸钠, 硫酸氨基葡萄糖, 膝骨关节炎, 临床疗效, 关节镜

Abstract: ［Abstract］ Objective To investigate the curative effect of arthroscope combined with sodium glassate and Glucosamine sulfate in the treatment of knee osteoarthritis （KOA）. Methods Seventy?eight patients with knee osteoarthritis were included in this study from January 2017 to March 2018. They were randomized into experimental group and control group. The patients （n=39） in experimental group underwent the management of arthroscope combined with sodium glassate and glucosamine sulfate， and the controls （n=39） was treated with arthroscopic surgery alone. Both groups were guided to perform knee functional exercise after surgery. VAS pain quantification score， Lequesne index and arthritic effect scale （AIMS） score were recorded and compared between the two groups before treatment， 2 weeks and 8 weeks after treatment. The clinical efficacy in two groups was analyzed， and the adverse reactions during the treatment were observed and recorded. Results In the experimental group and control group， there were significant differences in VAS score， Lequesne index and AIMS score before and 2 week and 8 week after treatment （all P values <0.05）. And as compared with control group， VAS score， Lequesne index and AIMS score in the experimental group showed significant differences in each time point （all P values <0.05）. Conclusion The joint arthroscope combined with sodium glassate and Glucosamine sulfate has a good effect on KOA and is superior to the single arthroscopic operation.

Key words: joint arthroscope, knee osteoarthritis, sodium vitreate, clinical efficacy, glucosamine sulfate