关键词: 后路腰椎椎体间融合术, 滑脱, 微创经椎间孔腰椎椎体间融合术, 疗效, 显微镜

Abstract: ［Abstract］ Objective To analyze and compare the outcomes in treatment of single level lumbar spondylolisthesis for Wiltse IV with MIS?TLIT （minimally invasive transforaminal lumbar interbody fusion， MIS?TLIT group） under a microscope and PLIF （posterior lumbar interbody fusion， PLIF group）. Methods This was a retrospective study and analyzed the clinical data of 128 cases of patients with single level lumbar spondylolisthesis for Wiltse IV. The perioperative indicators between the two groups （intraoperative blood loss， operative time， postoperative wound drainage for 48 hours after surgery） were recorded and compared. VAS score， JOA score and ODI score at preoperative levels， and in 2 weeks， 3， 6 and 24 months after surgery respectively were compared between MIS?TLIT group and PLIF group during the two years of follow?up. Results There was no significant difference between MIS?TLIT group and PLIF groups in operative time（P>0.05）. The intraoperative blood loss， postoperative wound drainage for 48 hours after surgery in MIS?TLIF were significantly lower than in PLIF group（P<0.05）. The significant differences were showed in VAS and ODI score between two groups and the patients in MIS?TLIF group were significantly lower than in PLIF group， but the JOA score of MIS?TLIF group was higher than that of PLIF group in 2 weeks after operation （P<0.05）. The differences of VAS， JOA score and ODI score between two groups were no significant differences in 3， 6， 24 months after operation（P<0.05）. Conclusion Compared with PLIF， microscopical MIS?TLIF treatment of single level lumbar spondylolisthesis for Wiltse IV has less trauma， less blood loss， significant short?term curative efficacy and similar long?term efficacy.

Key words: spondylolisthesis, microscope, minimal invasive posterior transforaminal lumbar interbody fusion, posterior lumbar interbody fusion, efficacy