关键词: 骨髓脂肪组织, 代谢性疾病, 细胞因子, 磁共振成像

Abstract: ［Abstract］ Bone strength is not only related to bone mineral density （BMD） and bone microarchitecture but also affected by the bone marrow microenvironment. Marrow adipose tissue （MAT） coexists with trabecular bonehematopoietic cells， nerve fibers and blood vessels in the medullary cavity， which plays an important role in bone remodeling， bone marrow hematopoiesis， and maintaining the stability of the bone marrow microenvironment. Recent studies have shown that MAT can participate in the development of various diseases such as metabolic diseases， hematological cancers and solid tumors by secreting cytokines such as adiponectin， providing new ideas for disease prevention， treatment and monitoring. Herein we review the biological characteristics and imaging methods of MAT， the correlation between MAT and disease and underlying mechanism.

Key words: cytokine, metabolic diseases, marrow adipose tissue, magnetic resonance imaging