关键词: R15, 静脉注射, K 值, 肝储备功能测定

Abstract: Department of Hepatic Surgery，Guangzhou First People′s Hospital，Guangzhou 510180，China Objective To evaluate the three different intravenous injections for the determination of liver function. Methods We selected 100 patients with internal jugular vein catheter to assess liver function by indocyanine green （ICG） injection. Each patient received all three different kinds of intravenous drug injection method respectively for testing. Then we compared three methods of determination on K and R15 values to check if they have significant difference statistically. Method one：liquid medicine was pushed by injection with the cubital vein indwelling needle followed with the pipe saline washing immediately ；Method 2 ：the volume of liquid medicine was increased by 0.4 mL with cubital vein indwelling needle without pipe saline washing. Method three：medicine injection was through the jugular vein pipe without pipe saline washing. Results The K and R15 values showed no significant difference statistically among three methods. The peak of blood concentration of Method 3 occurred earlier ，but not affect the final test results. Conclusion The three intravenous injection methods for the determination of liver function can successfully complete the administration process，and their results were close to the data，but the central venous catheter was better.

Key words: determination of liver reserve function, K value, intravenous injection, R15