关键词: 射频消融, 氩氦刀冷冻消融, 肝癌

Abstract: Objective To investigate the clinical value of cryoablation and cold tip radiofrequency ablation（RFA）in the treatment of malignant liver tumors. Methods Ultrasound guided cryoablation with argon?helium knife was performed in 38 patients with 42 lesions，and ultrasound?guided RFA was performed in 40 patients with 44 lesions.Before and after treatment ，contrast enhanced ultrasound ， enhanced CT or enhanced MRI examination were used to confirm the diagnosis and evaluate the curative effect. Results 32 lesions were completely ablated after one?time cryoablation，10 lesions were completely ablated after another?time cryoablation，33 lesions were completely ablated after one?time RFA，and 11 lesions were completely ablated after another?time RFA. The total ablation rate was 76.2%（cryoablation） and 75%（RFA）respectively，and the difference was not statistically significant. Conclusion Argonhelium cryoablation and cold?circulating RFA can effectively inactivate liver cancer in situ ，which is one of the effective non?surgical methods for the treatment of malignant liver tumors.

Key words: liver cancer, argon helium cryoablation, radiofrequency