关键词: 鸡尾酒注射, 骨性关节炎, 镇痛, 全膝关节置换

Abstract: ［Abstract］ Objective This study aims to explore the effectiveness of pain control of intraoperative periarticular multimodal injection in total knee arthroplasty for patients of osteoarthritis. Methods Sixty patients of knee osteoarthritis undergoing unilateral primary total knee arthroplasty were divided into injection group and control group. The patients were observed and followed at 48 hours, 1 week, one month, three months, and six months postoperatively. The Visual Analogue Scale（VAS）, Range of motion （ROM）、American Knee Society Score （KSS）, patient satisfaction, side effects and wound complications were recorded and statistically analyzed. Results There was a lower VAS in the injection group 48hours and one week after TKA（P<0.05）. A larger range of motion, a higher KSS and satisfaction rate were observed 48hours and one week postoperatively（P<0.05）. None of the indexes above were found statistically significant at one month, three months or six months postoperatively. No wound complication occurred. Conclusion Periarticular multimodal injection is effective in pain control after TKA in the early period, and it brings early function recovery, better inpatient experience, higher satisfaction rate, and faster rehabilitation eventually.

Key words: osteoarthritis, periarticular multimodal injection, total knee arthroplasty, pain control