关键词: Tao Brush, 子宫内膜癌, 筛查, Pipelle

Abstract: ［Abstract］ Objectives To compare the diagnostic value of Pipelle endometrial sampler and Tao brush endometrial sampler in endometrial cancer screening. Method 200 patients with abnormal uterine bleeding had endometrial sampling with randomly either Pipelle，or Tao brush sampler，were compared with D&C as gold standard，in the department of Obstetrics and Gynecology Unit，the Second Hospital of Shen Zhen，China，during the period of July 2015?July，2017. Pain score（VAS），bleeding volume，adequacy of samples and patient s compliance were also compared between the two groups. Results There was no significantly difference in the diagnostic accuracy between two groups（P>0.05）， with a correlations of both 98% compared with D&C； and the patients factors in bleeding volume， VAS， sample adequacy and complications were matched with no statistic significance （P>0.05）. Respectively，the sensitivity and specificity of two groups was 95.0% ，93.1% ，96.0% and 93.9% respectively；and the positive predictive value and the negative predictive value was 96.0% ，93.0% ， 95.0% and 93.0% ，respectively in each group. It s indicated that there is no significant difference in accuracy between Tao brush and Pipelle biopsy compared with D&G as gold standard in diagnosing（P> 0.05）. Conclusion It is concluded that both Tao brush and Pipelle biopsy are useful and cost?effective sampler methods compared with D&C，whist Tao brush perhaps has higher accuracy by taking biopsy for the patient thereby for early diagnosis of malignancy.

Key words: Tao Brush, endometrial cancer, screening, pipelle