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岭南现代临床外科 ›› 2018, Vol. 18 ›› Issue (02): 146-149.DOI: 10.3969/j.issn.1009-976X.2018.02.006

• 论著与临床研究 • 上一篇    下一篇

乳腺超声及X线检查在鉴别乳腺导管原位癌是否伴微浸润中的价值

王红莉1,林锦江2,赖建国1,顾然1,杨雅平1,谭翠1,刘凤桃1,蒋小芳1,胡越1,申时雨1,梅静思1,苏逢锡1*   

  1. 中山大学孙逸仙纪念医院
  • 通讯作者: 苏逢锡
  • 基金资助:

    国家自然科学基金面上项目

Sonographic and mammographic features to distinguish DCIS and DCIS with microinvasion

WANG Hongli1, LIN Jinjiang2, LAI Jianguo1, GU Ran1, YANG Yaping1, TAN Cui1, LIU Fengtao1, JI-ANG Xiaofang1, HU Yue1, SHEN Shiyu1, MEI Jingsi1, SU Fengxi1*   

  1. 1. Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510289, China;2. Department of Radiology, The First Affiliated Hospital of Sun Yat?sen University, Guangzhou 510080, China
  • Online:2018-04-20 Published:2018-04-20
  • Contact: SU Fengxi

摘要:

目的 比较导管原位癌(DCIS)及导管原位癌伴微浸润(DCISM)超声及X线特征的差异。方法 经手术病理诊断为DCIS和DCISM的病例共147例(DCIS94例,DCISM53例)。超声上,病变分为肿块及非肿块。X线上,病变分为单纯钙化、肿块、局灶不对称或结构扭曲。统计分析采用χ2检验,Fisher确切概率法及多因素logistic回归分析。结果 单因素及多因素分析结果显示,超声上病变内可见钙化及血流提示DCISM可能(P=0.038,P=0.025)。此外,X线上钙化范围越大,DCISM可能性越高(P=0.002)。结论 与DCIS相比,超声上病变内可见钙化及血流、X线上钙化分布范围较大与DCISM相关。

关键词: 微浸润, 超声, 乳腺X线摄影, 导管原位癌

Abstract:

Objective To compare the sonographic and mammographic features in patients with ductal carcinoma in situ(DCIS)and DCIS with microinvasion(DCISM). Methods A total of 147 women (94 DCIS and 53 DCISM) were retrospectively included. The sonographic lesions were classified as either masses or non-mass abnormalities. The lesions on mammography were classified as calcifications only, mass, asymmetry or architectural distortion. Statistical comparisons were made using Mann?Whitney U test, χ2 test, Fisher′s exact test and multiple logistic regression analysis. Results Univariate and multivariate analyses showed that the presence of microcalcifications and vascularity on sonography were associated with DCISM(P=0.038, P=0.025). Moreover, a greater range of calcification distribution were associated with a higher likelihood of DCISM(P=0.002). Conclusion The presence of microcal-cifications and vascularity on sonography or a great range of microcalcification distribution on mammo-graphy may suggest DCISM.

Key words: sonography, breast ductal carcinoma in situ, mammography, microinvasion

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