关键词: PTBD, 疗效与安全性 , 手术, 肝门部胆管癌

Abstract:

 Objective To investigate the effect and safety of preoperative percutaneous transhe-patic biliary drainage（PTBD）for the patients with hilar cholangiocarcinoma underwent operative treat-ment. Methods A total of 56 patients with hilar cholangiocarcinoma underwent operative treatment between January 2006 and December 2016, in whom 32 patients were subjected to PTBD before surgery （PTBD group）and 24 patients without PTBD were assigned to controls. The changes of the perioperative indicators were compared between two groups of patients. Results The total bilirubin of PTBD group was 286 ± 134 umol/L before PTBD treatment, which was significantly reduced to 153 ± 96 μmol/L after treatment （P<0.05）. Moreover there was no significant difference of the incidence with blood loss intraoperative, the bacteria infection of bile and postoperative complications between the two groups. Conclusion PTBD is a safe and effective method to alleviate jaundice for the patients with hilar cholan-giocarcinoma before operation, which can improve the patient’s liver function, systemic general situation and the tolerance of the surgery.

Key words: hilar cholangiocarcinoma, PTBD, operation, effect and safety