关键词: 舒洛地特, Villalta’s评分, 下肢深静脉血栓后遗症

Abstract: 【Abstract】〓Objective〓To explore the effect of oral sulodexide combined with melilotus extract tablet on post-thrombotic syndrome (PTS). Methods〓Thirty-four cases with PTS were included in the study from March 2015 to December 2015, in which 18 cases were treated with oral sulodexide combined with melilotus extract tablet (observation group) and 16 were taken melilotus extract tablet alone. The clinical effect was evaluated by the Villalta’s score. Results〓The therapeutic effect of subjective symptoms in the suffering limbs, such as symptomatic pain and paresthesia (heaviness, numbness, itching and discomfort) in the observation group had a great improvement as compared with the control group (symptomatic pain: 14/77.78% vs 6/37.5%, P=0.016; paresthesia: 14/77.78% vs 7/43.75%, P=0.040). The objective indicators, including skin irritation and redness, tenderness of gastrocnemius muscle also showed obvious improvement (4/25%, 15/83.33% vs P=0.01). Conclusion Oral sulodexide combined with melilotus extract tablet can facilitate post-thrombotic syndrome to achieve better clinical effect.

Key words: Post-thrombotic syndrome, Villalta’s scoring, Sulodexide