关键词: 动脉内灌注, 介入治疗, 脂源性, 胰腺炎

Abstract: 【Abstract】〓Objective〓To investigate the effect of continuous regional artery perfusion (CRAI) on treating acute severe lipid-induced pancreatitis. Methods〓Forty-three patients with severe lipid-induced pancreatitis patients admitted to our hospital from January 2013 to May 2016 were assigned to two groups, CRAI group (n=23) and control group (n=20). The patients of CRAI group received conventional treatment combined with conventional treatment and controls were performed the conventional treatment protocol alone. The levels of white blood cell count, amylase, blood sugar, blood calcium were collected in two groups and compared between two groups. The abdominal pain relief time, serum amylase recovery time, the hospitalization stay and expenses, peripancreatic infection incidence of pancreatic pseudocyst were compared between two groups. Results〓In CRAI group, the levels of serum amylase, urinary amylase, blood glucose on the sixth day, the first ten days of recovery were faster back to normal than that in conventional group, so did the blood calcium recovery time. Abdominal pain relief time, hospitalization stay, incidence of infection, pancreatic pseudocyst, pancreatic drainage in CRAI group were decreased than in normal group. Two cases were dead in control group and there were no death in CRAI group. Conclusion〓In the present study, CRAI was demonstrated a good efficacy in the treatment of severe acute pancreatitis, selected as an alternative treatment plan in combination with treatment protocol.

Key words: Acute pancreatitis, Interventional therapy, Intraartery infusion, Lipid-induced