关键词: 结直肠肿瘤, 幽门螺杆菌

Abstract: 【Abstract】 Objective To investigate the relationship of Helicobacter pylori (HP) with colorectal carcinoma. Methods〓212 cases of colorectal carcinoma specimens and 100 cases of normal colorectal mucosa specimens were studied, with routine HE staining and immunohistochemical staining for the detecting HP. Results〓Eight in 100 cases of normal colorectal mucosa tissues were detected HP, of which inoculation amount was small to moderate. Ninety-two in 212 cases of colorectal carcinoma cases were detected HP, in which small amount of HP were detected in 44 cases, moderate amount of HP in 37 cases, massive amount of HP in 11 cases. HP were independent to gender, the degree of tumor differentiation, TNM stage and related to the locations of the tumor. Conclusion〓HP may be the causative factor of colorectal carcinoma.

Key words: Colorectal neoplasms, Helicobacter pylori