关键词: 深静脉血栓, 老年, 髋关节置换, 髋部骨折, D-二聚体, ROC曲线

Abstract: 【Abstract】〓Objective〓To investigate plasma D-dimer in predicting the formation of deep vein thrombosis (DVT) in perioperative elderly patients with hip fracture. Methods〓A data of 202 patients with hip fracture in our hospital from 2010 to 2015 (elder than 60 years old) were analyzed, and 15 of them suffered from deep venous thrombosis of lower limbs. The D-dimer levels were measured in patients pre-operatively and postoperatively on day 1 to day 5, day 6 to day 10 by Color Doppler ultrasonography and contrast enhanced chest CT scan. SPSS19.0 software was applied to draw ROC curve for statistical analysis. Results〓By the ROC curve, the curve of the postoperative day 1 to day 5 D-dimer showed the largest AUC (0.85). Levels of the postoperative day 1 to day 5 were more valuable in the prediction of DVT. The best diagnostic point was located in the left upper corner of the ROC curve,which means the plasma D-dimer exceeded 1583 μg/L,and the prediction sensitivity was 80%,the specificity was 98%. Conclusion〓According to the ROC curve,elderly patients with plasma D-dimer more than 1583 μg/L in one to five days after hip replacement indicate a higher risk of DVT,regularly review of leg veins with color Doppler ultrasound examination is necessary.

Key words: Deep vein thrombosis, Hip fracture, Hip arthroplasty, ROC Curve, D-dimer, Old age