关键词: 应激性高血糖, 肠内营养, 重型颅脑损伤

Abstract: 【Abstract】〓Objective〓To investigate the role of early enteral nutrition in severe head injury patients with stress hyperglycemia. Methods〓Sixty cases of severe head injury complicated with stress hyperglycemia were recruited and a retrospective analysis from these patients was performed. According to the given enteral nutrition time,.the patients were divided into early enteral nutrition group (beginning from 8 hours after admission, n=30) and delayed enteral nutrition group (beginning from 48 hours after admission,.n=30)..Quality in evaluating diabetes control, hypoglycemia, and complications were observed and analyzed. Results〓Compared with delayed enteral nutrition group, the patients in early nutrition group displayed more reasonable average blood glucose after seven days of enteral nutrition, shorter the duration of insulin use and lower the occurrence of hypoglycemia (P<0.05). Meanwhile, the incidence of pulmonary infection was also lower in early enteral nutrition group than in delayed enteral nutrition group (P<0.05). There were no statistical significance in gastrointestinal hemorrhage, ventilation time and 28-day mortality. Conclusion〓The present findings indicate the early enteral nutrition can effectively improve the stress hyperglycemia and the hospital infection after severe head injury, but not bring beneficial effects on prognosis.

Key words: Stress hyperglycemia, Enteral nutrition, Severe traumatic brain injury