关键词: 脓毒症, 血清淀粉样蛋白A, 降钙素原, 诊断

Abstract: 【Abstract】〓Objective〓To investigate the diagnostic value of serum amyloid A(SAA) by comparison between SAA and procalcitonin (PCT). Methods〓Sixty-eight patients with sepsis were included in the study and were divided into two groups according to final diagnosis, sepsis group and non-infectious origin of systemic inflammatory response syndrome group (SIRS group). Serum SAA and PCT levels were determined and evaluated diagnostic significance by receiver operating characteristic curves (ROC). Results〓The levels of serum SAA and PCT in septic patients were significantly increased than that in non-infectious SIRS patients (P<0.001). Areas under ROC of SAA and PCT in the diagnosis of sepsis were 0.773±0.057 in SAA, 0.938±0.026 in PCT (SAA versus PCT,P<0.05). The accurate diagnostic rate of SAA was 70.6% and PCT 85.3%, while there were significant difference between them. Conclusion〓SAA, PCT have a same value for diagnosis of sepsis, but the later has advantage over the former.

Key words: Sepsis, Serum amyloid A, Procalcitonin, Diagnosis